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Article

MirSNP, a database of polymorphisms altering miRNA target sites, identifies miRNA-related SNPs in GWAS SNPs and eQTLs.

BMC genomics - 23 Nov 2012

Liu Chenxing, Zhang Fuquan, Li Tingting, Lu Ming, Wang Lifang, Yue Weihua, Zhang Dai

Abstract excerpt

BACKGROUND: Numerous single nucleotide polymorphisms (SNPs) associated with complex diseases have been identified by genome-wide association studies (GWAS) and expression quantitative trait loci (eQTLs) studies. However, few of these SNPs have explicit biological functions. Recent studies indicated that the SNPs within the 3'UTR regions of susceptibility genes could affect complex traits/diseases by affecting the...

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PMID: 23173617
DOI: 10.1186/1471-2164-13-661
PMCID: PMC3582533

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