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Article

Non-heritable genetics of human disease: spotlight on post-zygotic genetic variation acquired during lifetime.

Journal of medical genetics - 1 Jan 2013

Forsberg Lars Anders, Absher Devin, Dumanski Jan Piotr

Abstract excerpt

The heritability of most common, multifactorial diseases is rather modest and known genetic effects account for a small part of it. The remaining portion of disease aetiology has been conventionally ascribed to environmental effects, with an unknown part being stochastic. This review focuses on recent studies highlighting stochastic events of potentially great importance in human disease-the accumulation of...

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Identifiers

PMID: 23172682
DOI: 10.1136/jmedgenet-2012-101322
PMCID: PMC3534255

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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