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Article

Suppression of activin A signals inhibits growth of malignant pleural mesothelioma cells.

British journal of cancer - 4 Dec 2012

Hoda M A, Münzker J, Ghanim B, Schelch K, Klikovits T, Laszlo V, Sahin E, Bedeir A, Lackner A, Dome B, Setinek U, Filipits M, Eisenbauer M, Kenessey I, Török S, Garay T, Hegedus B, Catania A, Taghavi S, Klepetko W, Berger W, Grusch M

Abstract excerpt

BACKGROUND: Activins control the growth of several tumour types including thoracic malignancies. In the present study, we investigated their expression and function in malignant pleural mesothelioma (MPM). METHODS: The expression of activins and activin receptors was analysed by quantitative PCR in a panel of MPM cell lines. Activin A expression was further analysed by immunohistochemistry in MPM tissue specimens...

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Identifiers

PMID: 23169291
DOI: 10.1038/bjc.2012.519
PMCID: PMC3516694

Genes

SMAD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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