Article
Extensive haplotype diversity in African American mothers and their cord blood units.
Tissue antigens - 1 Jan 2013
Tu B, Leahy N, Yang R, Cha N, Kariyawasam K, Hou L, Xiao Y, Masaberg C, Pulse-Earle D, Maiers M, Ng J, Kurtzberg J, Hurley C K
Abstract excerpt
HLA-A, -B, -C, -DRB1, -DQB1 assignments were obtained for 374 pairs of African American mothers and their umbilical cord blood units (CBU) by DNA sequencing. An algorithm developed by the National Marrow Donor Program was used to assign 1122 haplotypes by segregation. Seventy percent of the haplotypes carried assignments at all five loci. In the remainder, alleles at various loci, most often DQB1 in 48% of the...
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