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Article

Phosphorylation of dopamine transporter serine 7 modulates cocaine analog binding.

The Journal of biological chemistry - 4 Jan 2013

Moritz Amy E, Foster James D, Gorentla Balachandra K, Mazei-Robison Michelle S, Yang Jae-Won, Sitte Harald H, Blakely Randy D, Vaughan Roxanne A

Abstract excerpt

As an approach to elucidating dopamine transporter (DAT) phosphorylation characteristics, we examined in vitro phosphorylation of a recombinant rat DAT N-terminal peptide (NDAT) using purified protein kinases. We found that NDAT becomes phosphorylated at single distinct sites by protein kinase A (Ser-7) and calcium-calmodulin-dependent protein kinase II (Ser-13) and at multiple sites (Ser-4, Ser-7, and Ser-13) by...

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Identifiers

PMID: 23161550
DOI: 10.1074/jbc.M112.407874
PMCID: PMC3537014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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