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Article

Lower susceptibility to cerebral small vessel disease in human familial longevity: the Leiden Longevity Study.

Stroke - 1 Jan 2013

Altmann-Schneider Irmhild, van der Grond Jeroen, Slagboom P Eline, Westendorp Rudi G J, Maier Andrea B, van Buchem Mark A, de Craen Anton J M

Abstract excerpt

BACKGROUND AND PURPOSE: On MRI, cerebral white matter lesions, lacunar infarcts, and cerebral microbleeds are common imaging correlates of cerebral small vessel damage in apparently healthy elderly individuals. We investigated whether middle-aged to elderly offspring of nonagenarian siblings, who are predisposed to become long-lived as well, have a lower prevalence of white matter lesions, lacunar infarcts, and...

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Identifiers

PMID: 23160879
DOI: 10.1161/STROKEAHA.112.671438

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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