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Burden of Dilated Perivascular Spaces, an Emerging Marker of Cerebral Small Vessel Disease, Is Highly Heritable.

Stroke - 1 Feb 2018

Duperron Marie-Gabrielle, Tzourio Christophe, Sargurupremraj Muralidharan, Mazoyer Bernard, Soumaré Aïcha, Schilling Sabrina, Amouyel Philippe, Chauhan Ganesh, Zhu Yi-Cheng, Debette Stéphanie

Abstract excerpt

BACKGROUND AND PURPOSE: The genetic contribution to dilated perivascular space (dPVS) burden-an emerging MRI marker of cerebral small vessel disease-is unknown. We measured the heritability of dPVS burden and its shared heritability with other MRI markers of cerebral small vessel disease. METHODS: The study sample comprised 1597 participants from the population-based Three City (3C) Dijon Study, with brain MRI...

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PMID: 29311265
DOI: 10.1161/STROKEAHA.117.019309

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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