Article
New tools for studying osteoarthritis genetics in zebrafish.
Osteoarthritis and cartilage - 1 Feb 2013
Mitchell R E, Huitema L F A, Skinner R E H, Brunt L H, Severn C, Schulte-Merker S, Hammond C L
Abstract excerpt
OBJECTIVE: Increasing evidence points to a strong genetic component to osteoarthritis (OA) and that certain changes that occur in osteoarthritic cartilage recapitulate the developmental process of endochondral ossification. As zebrafish are a well validated model for genetic studies and developmental biology, our objective was to establish the spatiotemporal expression pattern of a number of OA susceptibility...
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