Article

Zebrafish type I collagen mutants faithfully recapitulate human type I collagenopathies

2018-01-11

Abstract excerpt

<h4>ABSTRACT</h4> The type I collagenopathies are a group of heterogeneous connective tissue disorders, that are caused by mutations in the genes encoding type I collagen and include specific forms of Osteogenesis Imperfecta (OI) and the Ehlers-Danlos syndrome (EDS). These disorders present with a broad disease spectrum and large clinical variability of which the underlying genetic basis is still poorly understoo...

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Literature Corpus work: 9cf87ed4-4100-569f-b007-607ef1b50af9
DOI: 10.1101/247023

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