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Article

The effect of cigarette smoke and arsenic exposure on urothelial carcinoma risk is modified by glutathione S-transferase M1 gene null genotype.

Toxicology and applied pharmacology - 15 Jan 2013

Chung Chi-Jung, Huang Chao-Yuan, Pu Yeong-Shiau, Shiue Horng-Sheng, Su Chien-Tien, Hsueh Yu-Mei

Abstract excerpt

Inter-individual variation in the metabolism of xenobiotics, caused by factors such as cigarette smoking or inorganic arsenic exposure, is hypothesized to be a susceptibility factor for urothelial carcinoma (UC). Therefore, our study aimed to evaluate the role of gene-environment interaction in the carcinogenesis of UC. A hospital-based case-control study was conducted. Urinary arsenic profiles were measured...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromatography, High Pressure Liquid

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Source

Identifiers

PMID: 23159782
DOI: 10.1016/j.taap.2012.11.005

Genes

GSTM1
EPHX1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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