Article
Genetic sequence variants are associated with severity of lower urinary tract symptoms and prostate cancer susceptibility.
The Journal of urology - 1 Mar 2013
Helfand Brian T, Hu Qiaoyan, Loeb Stacy, McVary Kevin T, Catalona William J
Abstract excerpt
PURPOSE: While a clear heritable component underlies lower urinary tract symptoms and benign prostatic hyperplasia, few studies have identified specific genetic factors. In contrast, recent genome-wide association studies identified single nucleotide polymorphisms that increase prostate cancer risk. Some of these single nucleotide polymorphisms may also predispose to surgical intervention for benign prostatic...
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