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Article

A large-scale multi-ancestry genome-wide association study of chronic prostatitis/chronic pelvic pain syndrome in men.

Nature communications - 9 Jan 2026

Rosenthal Sara Brin, Maihofer Adam X, Nievergelt Caroline M, Dochtermann Daniel, Gerstenberger Armand, Whisenant Thomas, Pyarajan Saiju, Allen-Brady Kristina, Krieger John N, Afari Niloofar, Gasperi Marianna

Abstract excerpt

Chronic prostatitis/chronic pelvic pain syndrome is common, and it impacts men's health and quality of life. The genetic basis of this condition remains largely unknown. Here, we conduct a GWAS using data from the Million Veteran Program of over 590,000 men of European, African, and Hispanic ancestry, including 14,575 chronic prostatitis/chronic pelvic pain syndrome cases. The multi-ancestry analysis identifies...

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Black or African American
Chronic Disease
Chronic Pain
Hispanic or Latino
Mendelian Randomization Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Prostatic Hyperplasia

Prostatic Neoplasms

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Identifiers

PMID: 41513650
DOI: 10.1038/s41467-025-64954-2
PMCID: PMC12789528

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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