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Article

Refining the diagnosis and prognostic categorization of acute myeloid leukemia patients with an integrated use of cytogenetic and molecular studies.

Acta haematologica - 1 Jan 2013

Costa Dolors, Vidal Anna, Carrió Ana, Muñoz Concha, Arias Amparo, Gómez Cándida, Berneaga Daniela, Colomer Dolors, Rozman Maria, Pratcorona Marta, Torrebadell Montserrat, Díaz-Beyá Marina, Esteve Jordi, Campo Elías

Abstract excerpt

Significant progress in the understanding of the genetic basis of acute myeloid leukemia (AML) has been made during the last 30 years. The aim of the present study was to assess whether the detection of recurrent gene rearrangements by fluorescent in situ hybridization (FISH) studies and NPM1 and FLT3 gene mutations by molecular studies added clinically relevant information to the karyotype in 113 AML patients....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23154527
DOI: 10.1159/000343616

Genes

FLT3
NPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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