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Article

The added values of multiplex reverse transcriptase-PCR followed by mutation screening in the initial evaluation of acute leukemia.

International journal of laboratory hematology - 1 Aug 2016

Kim B, Cho Y-U, Bae M-H, Jang S, Seo E-J, Chi H-S, Park C-J

Abstract excerpt

INTRODUCTION: This study investigates the benefits of using multiplex reverse transcriptase-PCR (RT-PCR) in addition to standard karyotyping during the initial evaluation of acute leukemia. METHODS: A total of 1114 consecutive specimens from patients with acute leukemia were tested using a commercial multiplex RT-PCR kit (HemaVision, DNA Diagnostic). NPM1 and CEBPA mutations were selectively tested in acute...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukemia

Share to Leukemia, Myeloid, Acute

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Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

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Share to Translocation, Genetic

Source

Identifiers

PMID: 27321126
DOI: 10.1111/ijlh.12521

Genes

NPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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