Article
The role of molecular tests in acute myelogenous leukemia treatment decisions.
Current hematologic malignancy reports - 1 Apr 2010
Motyckova Gabriela, Stone Richard M
Abstract excerpt
The prognosis for patients with acute myelogenous leukemia (AML) is dependent on age, karyotype, and the genetics of the neoplastic cell. The molecular markers with prognostic impact include mutations in FLT3, NPM1, MLL, WT1, c-KIT, and expression levels of BAALC, NM1, ERG, and CXCR4. Gene expression profiles and microRNA expression patterns in AML may prove highly useful in defining the prognosis of AML....
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