Article
Functional analysis of the human tissue factor promoter and induction by serum.
Proceedings of the National Academy of Sciences of the United States of America - 1 Mar 1990
Mackman N, Fowler B J, Edgington T S, Morrissey J H
Abstract excerpt
Tissue factor (TF) is the primary initiator of the coagulation protease cascades. This cell surface glycoprotein is the receptor and essential cofactor for the serine protease factor VIIa. TF is constitutively expressed in some extravascular cell types and is transiently induced in monocytes, end...
Topics
- Animals
- Base Sequence
- Cell Line
- Chromosome Deletion
- Enhancer Elements, Genetic
- Exons
- Gene Expression Regulation
- Humans
- Kinetics
- Molecular Sequence Data
- Mutation
- Oligonucleotide Probes
- Promoter Regions, Genetic
- Thromboplastin
- Transfection