Article
Polymorphisms in the 5'-UTR of the tissue factor gene are associated with altered expression in human endothelial cells.
Journal of thrombosis and haemostasis : JTH - 1 Aug 2004
Terry C M, Kling S J, Cheang K I, Hoidal J R, Rodgers G M
Abstract excerpt
BACKGROUND: Enhanced tissue factor (TF) expression mediates many disease processes. Recently, four completely concordant polymorphisms were detected in the 5'-UTR of the TF gene. Three were single base changes and one was an 18-bp insertion/deletion at -1208. OBJECTIVES: This study was undertaken to determine if the I-allele or the D-allele would associate with elevated TF expression in human umbilical vein...
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