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Article

Cerebrolysin modulates pronerve growth factor/nerve growth factor ratio and ameliorates the cholinergic deficit in a transgenic model of Alzheimer's disease.

Journal of neuroscience research - 1 Feb 2013

Ubhi Kiren, Rockenstein Edward, Vazquez-Roque Ruben, Mante Michael, Inglis Chandra, Patrick Christina, Adame Anthony, Fahnestock Margaret, Doppler Edith, Novak Philip, Moessler Herbert, Masliah Eliezer

Abstract excerpt

Alzheimer's disease (AD) is characterized by degeneration of neocortex, limbic system, and basal forebrain, accompanied by accumulation of amyloid-β and tangle formation. Cerebrolysin (CBL), a peptide mixture with neurotrophic-like effects, is reported to improve cognition and activities of daily...

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Source

Identifiers

PMID: 23152192
DOI: 10.1002/jnr.23142

Genes

NGF
CBL
BDNF
CNTF
APP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23152192-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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