Article
[Relation of genetic polymorphism of XRCC1 with risks of chronic benzene poisoning].
Wei sheng yan jiu = Journal of hygiene research - 1 Sept 2004
Zhang Zhongbin, Cao Duozhi, Wan Junxiang, Gu Shouyong, Jin Xipeng, Xia Zhaolin
Abstract excerpt
OBJECTIVE: To explore the relation between genetic polymorphisms in XRCC1 and risks of chronic benzene poisoning (BP). METHODS: A case-control study was conducted. 152 BP patients and 152 workers occupationally exposed to benzene without poisoning manifestations were investigated. PCR-RFLP was applied to detect the single nucleotide polymorphisms (SNPs) on c.194, c.280 and c.399 of XRCC1 gene. RESULTS: The...
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