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MIF rs755622 and IL6 rs1800795 Are Implied in Genetic Susceptibility to End-Stage Renal Disease (ESRD).

Genes - 25 Jan 2022

Guarneri Marco, Scola Letizia, Giarratana Rosa Maria, Bova Manuela, Carollo Caterina, Vaccarino Loredana, Calandra Leonardo, Lio Domenico, Balistreri Carmela Rita, Cottone Santina

Abstract excerpt

Chronic kidney disease (CKD) is characterized by an increased risk of kidney failure and end-stage renal disease (ESRD). Aging and comorbidities as cardiovascular diseases, metabolic disorders, infectious diseases, or tumors, might increase the risk of dialysis. In addition, genetic susceptibility factors might modulate kidney damage evolution. We have analyzed, in a group of ESRD patients and matched controls, a...

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PMID: 35205271
DOI: 10.3390/genes13020226
PMCID: PMC8872268

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