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Article

Statistical distributions of test statistics used for quantitative trait association mapping in structured populations.

Genetics, selection, evolution : GSE - 12 Nov 2012

Teyssèdre Simon, Elsen Jean-Michel, Ricard Anne

Abstract excerpt

BACKGROUND: Spurious associations between single nucleotide polymorphisms and phenotypes are a major issue in genome-wide association studies and have led to underestimation of type 1 error rate and overestimation of the number of quantitative trait loci found. Many authors have investigated the influence of population structure on the robustness of methods by simulation. This paper is aimed at developing further...

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Identifiers

PMID: 23146127
DOI: 10.1186/1297-9686-44-32
PMCID: PMC3817592

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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