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Article

Cry1Aa binding to the cadherin receptor does not require conserved amino acid sequences in the domain II loops.

Bioscience reports - 20 Dec 2012

Fujii Yuki, Tanaka Shiho, Otsuki Manami, Hoshino Yasushi, Morimoto Chinatsu, Kotani Takuya, Harashima Yuko, Endo Haruka, Yoshizawa Yasutaka, Sato Ryoichi

Abstract excerpt

Characterizing the binding mechanism of Bt (Bacillus thuringiensis) Cry toxin to the cadherin receptor is indispensable to understanding the specific insecticidal activity of this toxin. To this end, we constructed 30 loop mutants by randomly inserting four serial amino acids covering all four receptor binding loops (loops α8, 1, 2 and 3) and analysed their binding affinities for Bombyx mori cadherin receptors...

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Identifiers

PMID: 23145814
DOI: 10.1042/BSR20120113
PMCID: PMC3546355

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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