Complete genome and phenotypic characterization of a feline-derived Bartonella henselae strain with enhanced endothelial interaction and immunomodulatory phenotypes.

Abstract excerpt

Bartonella henselae is a zoonotic pathogen capable of persistent infection through endothelial interaction and modulation of host immune responses. We hypothesized that this feline-derived strain may retain the conserved B. henselae virulence framework while displaying distinct virulence-associated host-cell phenotypes. In this study, we report the complete genome of a feline-derived B. henselae strain,...

Topics

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• Cats
• Endothelial Cells
• Genome, Bacterial
• Host-Pathogen Interactions
• Immunomodulation