Relations of long-term and contemporary lipid levels and lipid genetic risk scores with coronary artery calcium in the framingham heart study.

doi:10.1016/j.jacc.2012.09.007

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Relations of long-term and contemporary lipid levels and lipid genetic risk scores with coronary artery calcium in the framingham heart study.

Journal of the American College of Cardiology - 11 Dec 2012

Tsao Connie W, Preis Sarah Rosner, Peloso Gina M, Hwang Shih-Jen, Kathiresan Sekar, Fox Caroline S, Cupples L Adrienne, Hoffmann Udo, O'Donnell Christopher J

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OBJECTIVES: This study evaluated the association of timing of lipid levels and lipid genetic risk score (GRS) with subclinical atherosclerosis. BACKGROUND: Atherosclerosis is a slowly progressive disorder influenced by suboptimal lipid levels. Long-term versus contemporary lipid levels may more strongly impact the development of coronary artery calcium (CAC). METHODS: Framingham Heart Study (FHS) Offspring Cohort...

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Relations of long-term and contemporary lipid levels and lipid genetic risk scores with coronary artery calcium in the framingham heart study.

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