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Article

Regulation of calcium influx and signaling pathway in cancer cells via TRPV6-Numb1 interaction.

Cell calcium - 1 Feb 2013

Kim Sung-Young, Yang Dongki, Myeong Jongyoun, Ha Kotdaji, Kim Su-Hwa, Park Eun-Jung, Kim In-Gyu, Cho Nam-Hyuk, Lee Kyu Pil, Jeon Ju-Hong, So Insuk

Abstract excerpt

Ca(2+) is a critical factor in the regulation of signal transduction and Ca(2+) homeostasis is altered in different human diseases. The level of Ca(2+) in cells is highly regulated through a diverse class of regulators. Among them is the transient receptor potential vanilloid 6 (TRPV6), which is a Ca(2+) selective channel that absorbs Ca(2+) in the small intestine. TRPV6 is overexpressed in some cancers and...

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Source

Identifiers

PMID: 23140583
DOI: 10.1016/j.ceca.2012.10.005

Genes

TRPV6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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