Article
Description of a new HLA-E (E*01031) allele and its frequency in the Spanish population.
Human immunology - 15 Apr 1997
Gomez-Casado E, Martinez-Laso J, Vargas-Alarcón G, Varela P, Diaz-Campos N, Alvarez M, Alegre R, Arnaiz-Villena A
Abstract excerpt
An HLA-E polymorphism study by oligotyping and DNA sequencing was carried out in the Spanish population. As a result, a new HLA-E allele (E*01031) initially assigned by polymerase chain reaction oligotyping as E*0104 was found. This allele presents a synonymous change at codon 77 (AAT-->AAC; Asn) when compared with the E*01032 allele. This position is located in the alpha-helix (alpha 1-domain) and is involved in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.