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Article

THRB genetic polymorphisms can predict severe myelotoxicity after definitive chemoradiotherapy in patients with esophageal squamous cell carcinoma.

International journal of medical sciences - 1 Jan 2012

Miki Ikuya, Nakamura Tsutomu, Kuwahara Akiko, Yamamori Motohiro, Nishiguchi Kohshi, Tamura Takao, Okuno Tatsuya, Omatsu Hideaki, Mizuno Shigeto, Hirai Midori, Azuma Takeshi, Sakaeda Toshiyuki

Abstract excerpt

OBJECTIVE: Chemotherapy-related toxicities are difficult to predict before treatment. In this study, we investigated whether thyroid hormone receptor beta (THRB) genetic polymorphisms can serve as a potential biomarker in patients with esophageal squamous cell carcinoma (ESCC). METHODS: Forty-nine Japanese patients with ESCC who received a definitive chemoradiotherapy (CRT) with 5-fluorouracil and cisplatin in...

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Identifiers

PMID: 23136537
DOI: 10.7150/ijms.5081
PMCID: PMC3491433

Genes

THRB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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