Article
Induction Chemotherapy in Hypopharyngeal Cancer: Influence of DNA Repair Gene Polymorphisms.
Anticancer research - 1 Jun 2020
Hirakawa Hitoshi, Ikegami Taro, Azechi Satoe, Agena Shinya, Uezato Jin, Kinjyo Hidetoshi, Yamashita Yukashi, Kiyuna Asanori, Tanaka Katsunori, Kondo Shunsuke, Maeda Hiroyuki, Suzuki Mikio, Ganaha Akira
Abstract excerpt
BACKGROUND/AIM: The aim was to clarify whether DNA repair gene polymorphisms can be used to predict response to cisplatin, 5-fluorouracil, and docetaxel (TPF) as induction chemotherapy (ICT) in Japanese patients with hypopharyngeal cancer (HPC). MATERIALS AND METHODS: DNA repair gene polymorphisms (rs3212986, rs1799793, rs13181, and rs25487) were analyzed in 117 HPC patients and 125 control subjects by...
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