Article
[Association between polymorphisms of Pen2 gene and late onset Alzheimer's disease].
Zhonghua yi xue za zhi - 17 Jul 2012
Jia Long-fei, Lü Ji-hui, Ma Zhong-hua
Abstract excerpt
OBJECTIVE: To explore the association between single nucleotide polymorphisms (SNPs) in Pen2 gene and late onset Alzheimer's disease (LOAD) in North Chinese population. METHODS: The genotypes of ApoE and Pen2 gene were determined by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and direct sequencing respectively in 480 LOAD patients and 480 healthy controls. The strength of...
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