Article
Investigation of CD28 gene polymorphisms in patients with sporadic breast cancer in a Chinese Han population in Northeast China.
PloS one - 1 Jan 2012
Chen Shuang, Zhang Qing, Shen Liming, Liu Yanhong, Xu Fengyan, Li Dalin, Fu Zhenkun, Yuan Weiguang, Pang Da, Li Dianjun
Abstract excerpt
BACKGROUND: CD28 is one of a number of costimulatory molecules that play crucial roles in immune regulation and homeostasis. Accumulating evidence indicates that immune factors influence breast carcinogenesis. To clarify the relationships between polymorphisms in the CD28 gene and breast carcinogenesis, a case-control study was conducted in women from Heilongjiang Province in northeast of China....
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