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Article

Mechanism for epigenetic variegation of gene expression at yeast telomeric heterochromatin.

Genes & development - 1 Nov 2012

Kitada Tasuku, Kuryan Benjamin G, Tran Nancy Nga Huynh, Song Chunying, Xue Yong, Carey Michael, Grunstein Michael

Abstract excerpt

Yeast contains heterochromatin at telomeres and the silent mating-type loci (HML/HMR). Genes positioned within the telomeric heterochromatin of Saccharomyces cerevisiae switch stochastically between epigenetically bistable ON and OFF expression states. Important aspects of the mechanism of variegated gene expression, including the chromatin structure of the natural ON state and the mechanism by which it is...

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Source

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Identifiers

PMID: 23124068
DOI: 10.1101/gad.201095.112
PMCID: PMC3490002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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