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Article

Differential inhibition of neurogenesis and angiogenesis by corticosterone in rats stimulated with electroconvulsive seizures.

Progress in neuro-psychopharmacology & biological psychiatry - 1 Aug 2008

Ekstrand Joakim, Hellsten Johan, Wennström Malin, Tingström Anders

Abstract excerpt

Antidepressant drugs and electroconvulsive seizure (ECS)-treatment, an animal model of electroconvulsive therapy, induce neurogenesis in adult rats. Stress and high levels of corticosterone (CORT) on the contrary inhibit neurogenesis. Hippocampal neurogenesis has been described to occur in an angiogenic niche where proliferation of neural progenitors takes place in an environment with active vascular growth. Here...

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Source

Identifiers

PMID: 18583010
DOI: 10.1016/j.pnpbp.2008.05.012

Genes

CORT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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