Article
Investigation of Caucasian rheumatoid arthritis susceptibility loci in African patients with the same disease.
Arthritis research & therapy - 3 Nov 2012
Viatte Sebastien, Flynn Edward, Lunt Mark, Barnes Joanne, Singwe-Ngandeu Madeleine, Bas Sylvette, Barton Anne, Gabay Cem
Abstract excerpt
INTRODUCTION: The largest genetic risk to develop rheumatoid arthritis (RA) arises from a group of alleles of the HLA DRB1 locus ('shared epitope', SE). Over 30 non-HLA single nucleotide polymorphisms (SNPs) predisposing to disease have been identified in Caucasians, but they have never been investigated in West/Central Africa. We previously reported a lower prevalence of the SE in RA patients in Cameroon...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
