Alpha-1-antitrypsin (protease inhibitor) phenotypes and longevity.

doi:10.1159/000153897

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Article

Alpha-1-antitrypsin (protease inhibitor) phenotypes and longevity.

Human heredity - 1 Jan 1990

Muir A, Whitfield J B

Abstract excerpt

We have tested the hypothesis that the protease inhibitor phenotypes MZ and MS are disadvantageous and reduce survival by comparing the prevalence of these phenotypes in a group of 707 very old people (hospital patients) with the prevalences reported in younger populations of blood donors. The MS...

Topics

Aged
Aged, 80 and over
Aging
Alleles
Female
Gene Frequency
Heterozygote
Humans
Longevity
Male
Phenotype
alpha 1-Antitrypsin

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