Article
Alpha-1-antitrypsin (protease inhibitor) phenotypes and longevity.
Human heredity - 1 Jan 1990
Muir A, Whitfield J B
Abstract excerpt
We have tested the hypothesis that the protease inhibitor phenotypes MZ and MS are disadvantageous and reduce survival by comparing the prevalence of these phenotypes in a group of 707 very old people (hospital patients) with the prevalences reported in younger populations of blood donors. The MS and MZ phenotypes appear to be no less common among those who have survived to old age, but a highly significant...
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