The epidemiology of alpha 1-antitrypsin deficiency.

doi:10.1007/BF02718176

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Article

The epidemiology of alpha 1-antitrypsin deficiency.

Lung - 1 Jan 1990

Hutchison D C

Abstract excerpt

Alpha 1-protease inhibitor can exist as over 70 different biochemical variants (the Pi system) which are inherited as autosomal-codominant alleles. The majority of these variants are of no clinical significance. Epidemiologically, the most abundant are Pi types M, S, and Z. Homozygotes of type Z...

Topics

Asthma
Cross-Sectional Studies
Gene Frequency
Humans
Incidence
Liver Cirrhosis
Phenotype
Risk Factors
alpha 1-Antitrypsin
alpha 1-Antitrypsin Deficiency

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