Article
Purification and structure elucidation of the by-product of new regulator of antibiotic production and differentiation of Streptomyces.
Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993) - 1 Jan 2000
Matselyukh B, Mohammadipanah F, Laatsch H, Rohr J, Efremenkova O, Khilya V
Abstract excerpt
Streptomyces globisporus 1912, a producer of the antitumor antibiotic landomycin E, forms the new low-molecular signaling molecule N-methylphenylalanyl-dehydrobutyrine diketopiperazine (BDD) and its complex and unstable by-product which restore, like the A-factor in Streptomyces griseus 773, landomycin E and streptomycin biosynthesis, and sporulation of the defective mutants S. globisporus 1912-B2 and S. griseus...
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