Article
Mutation frequency and spectrum of mutations vary at different chromosomal positions of Pseudomonas putida.
PloS one - 1 Jan 2012
Juurik Triinu, Ilves Heili, Teras Riho, Ilmjärv Tanel, Tavita Kairi, Ukkivi Kärt, Teppo Annika, Mikkel Katren, Kivisaar Maia
Abstract excerpt
It is still an open question whether mutation rate can vary across the bacterial chromosome. In this study, the occurrence of mutations within the same mutational target sequences at different chromosomal locations of Pseudomonas putida was monitored. For that purpose we constructed two mutation detection systems, one for monitoring the occurrence of a broad spectrum of mutations and transposition of IS element...
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