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Article

Renal cell carcinoma and a constitutional t(11;22)(q23;q11.2): case report and review of the potential link between the constitutional t(11;22) and cancer.

Cancer genetics - 1 Nov 2012

Doyen Jérôme, Carpentier Xavier, Haudebourg Juliette, Hoch Benjamin, Karmous-Benailly Houda, Ambrosetti Damien, Fabas Thibault, Amiel Jean, Lambert Jean-Claude, Pedeutour Florence

Abstract excerpt

We observed a t(11;22)(q23-24;q11.2-12) and monosomy 3 in renal tumor cells from a 72-year-old man. The hypothesis of a primitive peripheral neuroectodermal tumor (PPNET) located in the kidney was promptly excluded: Histologically, the tumor was a clear cell renal cell carcinoma (RCC) and we did not observe an EWSR1 gene rearrangement. The constitutional origin of this alteration was established. We report on the...

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Share to Abnormal Karyotype
Share to Carcinoma, Renal Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 11

Share to Chromosomes, Human, Pair 22

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Source

Identifiers

PMID: 23117075
DOI: 10.1016/j.cancergen.2012.09.006

Genes

EWSR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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