Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Paternal origin of the de novo constitutional t(11;22)(q23;q11).

European journal of human genetics : EJHG - 1 Jul 2010

Ohye Tamae, Inagaki Hidehito, Kogo Hiroshi, Tsutsumi Makiko, Kato Takema, Tong Maoqing, Macville Merryn V E, Medne Livija, Zackai Elaine H, Emanuel Beverly S, Kurahashi Hiroki

Abstract excerpt

The constitutional t(11;22)(q23;q11) is a well-known recurrent non-Robertsonian translocation in humans. Although translocations generally occur in a random fashion, the break points of t(11;22)s are concentrated within several hundred base pairs on 11q23 and 22q11. These regions are characterize...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Chromosomes, Human, Pair 11
Share to Chromosomes, Human, Pair 22

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Family

Share to Parents

Share to Pedigree

Share to Polymerase Chain Reaction

Share to Translocation, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 20179746
DOI: 10.1038/ejhg.2010.20
PMCID: PMC2987363

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20179746-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Paternal origin of the de novo constitutional t(11;22)(q23;q11).PMID 20179746Read ↗

Polymorphisms of the 22q11.2 breakpoint region influence the frequency of de novo constitutional t(11;22)s in sperm.Semantic proximity Read ↗

The constitutional t(11;22): implications for a novel mechanism responsible for gross chromosomal rearrangementsSemantic proximity Read ↗

Genetic variation affects de novo translocation frequency.Semantic proximity Read ↗

A palindrome-mediated recurrent translocation with 3:1 meiotic nondisjunction: the t(8;22)(q24.13;q11.21).Semantic proximity Read ↗

Two different forms of palindrome resolution in the human genome: deletion or translocation.Semantic proximity Read ↗

[Palindromic sequence-mediated de novo chromosome translocation in sperm samples derived from normal and oligospermic males].Semantic proximity Read ↗

Molecular mechanisms and diagnosis of chromosome 22q11.2 rearrangements.Semantic proximity Read ↗

Clustered 11q23 and 22q11 breakpoints and 3:1 meiotic malsegregation in multiple unrelated t(11;22) families.Semantic proximity Read ↗

De novo dup p/del q or dup q/del p rearranged chromosomes: review of 104 cases of a distinct chromosomal mutation.Semantic proximity Read ↗

Meiotic Recombination and Spatial Proximity in the Etiology of the Recurrent t(11;22)Semantic proximity Read ↗

De novo apparently balanced translocations in man are predominantly paternal in origin and associated with a significant increase in paternal age.Semantic proximity Read ↗

A Novel Non-Allelic Homologous Recombination Event in a Parent with an 11;22 Reciprocal Translocation Leading to 22q11.2 Deletion Syndrome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.