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Article

Molecular cloning of a constitutional t(7;22) translocation associated with risk of hematological malignancy.

Genes, chromosomes & cancer - 1 Nov 2003

Hill Alexander S, MacCallum Peter K, Young Bryan D, Lillington Debra M

Abstract excerpt

We report the molecular characterization of a reciprocal constitutional translocation t(7;22)(p13;q11.2) carried by three family members who have each developed a hematological malignancy. The chromosome 7 breakpoint was localized to a single BAC clone, RP11-571N3, by sequential fluorescence in situ hybridization analysis of clones selected from the NCBI chromosome 7 map. This was further refined to a 739-bp...

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Share to Chromosomes, Human, Pair 22
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14506701
DOI: 10.1002/gcc.10277

Genes

IGL
IGFBP1
IGFBP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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