Article
Genetic Testing in Acute Myeloid Leukemia and Myelodysplastic Syndromes.
Surgical pathology clinics - 1 Mar 2016
Nardi Valentina, Hasserjian Robert P
Abstract excerpt
Cytogenetic analysis of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) is essential for disease diagnosis, classification, prognostic stratification, and treatment guidance. Molecular genetic analysis of CEBPA, NPM1, and FLT3 is already standard of care in patients with AML, and mutations in several additional genes are assuming increasing importance. Mutational analysis of certain genes, such as...
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