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Article

Myotubularin family phosphatase ceMTM3 is required for muscle maintenance by preventing excessive autophagy in Caenorhabditis elegans.

BMC cell biology - 31 Oct 2012

Yu Xiaokun, Ma Junfeng, Lin Feng, Zhao Wanke, Fu Xueqi, Zhao Zhizhuang Joe

Abstract excerpt

BACKGROUND: Autophagy is a ubiquitous cellular process responsible for the bulk degradation of cytoplasmic components through the autophagosomal-lysosomal pathway. In skeletal muscle, autophagy has been regarded as a key regulator for muscle mass maintenance, and its imbalance leads to sarcopenia. However, the underlying mechanism is poorly understood. RESULTS: In this study, we demonstrate that ceMTM3, a...

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Identifiers

PMID: 23114011
DOI: 10.1186/1471-2121-13-28
PMCID: PMC3506462

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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