Article
Molecular characterization, expression profiles, and association analysis with hematologic parameters of the porcine HPSE and HPSE2 genes.
Journal of applied genetics - 1 Feb 2013
Tao Cong, Wang Weimin, Zhou Ping, Xia Tian, Zhou Xiang, Zeng Cuiping, Zhang Qingde, Liu Bang
Abstract excerpt
Heparan sulfate (HS), which consists of repeating disaccharide units, plays an essential role in inflammation and viral infections. Heparanase (encoded by the HPSE gene) can cleave the HS chains of heparan sulfate proteoglycans (HSPGs), which are known to be important participants in immune responses. HPSE2 (heparanase 2) is a homologous gene of HPSE. To investigate the functions of HS, which is the primary...
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