Article
Expression patterns and association analysis of the porcine DHX58 gene.
Animal genetics - 1 Oct 2010
Li X Y, Han C M, Wang Y, Liu H Z, Wu Z F, Gao Q H, Zhao S H
Abstract excerpt
RIG-1 signalling is responsible for the detection of cytoplasmic viral RNA molecules. DEXH(Asp-Glu-X-His) box polypeptide 58 (encoded by DHX58) is a negative regulator of the RIG-1 signalling pathway. In human, the DHX58 gene can be upregulated and can inhibit the RIG-1 signalling pathway during viral infection. In this study, porcine DHX58 gene expression patterns were studied. According to our results, the...
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