Article
Polymorphic variants in exon 8 at the 3' UTR of the HLA-G gene are associated with septic shock in critically ill patients.
Critical care (London, England) - 29 Oct 2012
Graebin Pietra, Veit Tiago D, Alho Clarice S, Dias Fernando S, Chies José A B
Abstract excerpt
INTRODUCTION: Critically ill patients are characterized as individuals hospitalized in the Intensive Care Unit (ICU) and can evolve to sepsis, septic shock or even death. Among others, genetic factors can influence the outcome of critically ill patients. HLA-G is a non-classical class Ib molecule that has limited protein variability, presenting seven isoforms generated by alternative splicing, and presents...
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