The distribution of mutational fitness effects of phage φX174 on different hosts.

Abstract excerpt

Adaptation depends greatly on the distribution of mutation fitness effects (DMFE), but the phenotypic expression of mutations is often environment dependent. The environments faced by multihost pathogens are mostly governed by their hosts and therefore measuring the DMFE on multiple hosts can inform on the likelihood of short-term establishment and longer term adaptation of emerging pathogens. We explored this by...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Bacteriophage phi X 174
• Share to Evolution, Molecular