Article
Coevolution with bacteriophages drives genome-wide host evolution and constrains the acquisition of abiotic-beneficial mutations.
Molecular biology and evolution - 1 Jun 2015
Scanlan Pauline D, Hall Alex R, Blackshields Gordon, Friman Ville-P, Davis Michael R, Goldberg Joanna B, Buckling Angus
Abstract excerpt
Studies of antagonistic coevolution between hosts and parasites typically focus on resistance and infectivity traits. However, coevolution could also have genome-wide effects on the hosts due to pleiotropy, epistasis, or selection for evolvability. Here, we investigate these effects in the bacterium Pseudomonas fluorescens SBW25 during approximately 400 generations of evolution in the presence or absence of...
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