Developmental profile of hepatic alcohol and aldehyde dehydrogenase activities in long-sleep and short-sleep mice.

doi:10.1016/0741-8329(90)90062-h

Back to search

Article

Developmental profile of hepatic alcohol and aldehyde dehydrogenase activities in long-sleep and short-sleep mice.

Alcohol (Fayetteville, N.Y.) - 1 Jan 2000

Smolen T N, Smolen A, van de Kamp J L

Abstract excerpt

Ethanol is metabolized primarily in the liver by a cytosolic alcohol dehydrogenase (ADH). The product, acetaldehyde, is metabolized to acetate by nonspecific aldehyde dehydrogenases (AHD). Mouse liver contains five major constitutive AHD isoenzymes: mitochondrial high Km (AHD-1), mitochondrial lo...

Topics

Aging
Alcohol Dehydrogenase
Aldehyde Dehydrogenase
Animals
Cytosol
Ethanol
Female
Genotype
Isoenzymes
Liver
Male
Mice
Mice, Mutant Strains
Microsomes, Liver
Mitochondria, Liver
Sleep

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.