Article
Altered Metabolism during the Dark Period in Drosophila Short Sleep Mutants.
Journal of proteome research - 6 Sept 2024
Malik Dania M, Rhoades Seth D, Kain Pinky, Sengupta Arjun, Sehgal Amita, Weljie Aalim M
Abstract excerpt
Sleep is regulated via circadian mechanisms, but effects of sleep disruption on physiological rhythms, in particular metabolic cycling, remain unclear. To examine this question, we probed diurnal metabolic alterations of two Drosophila short sleep mutants, fumin and sleepless. Samples were collected with high temporal sampling (every 2 h) over 24 h under a 12:12 light:dark cycle, and profiling was done using an...
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