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Article

Chronic self-administration of alcohol results in elevated ΔFosB: comparison of hybrid mice with distinct drinking patterns.

BMC neuroscience - 29 Oct 2012

Ozburn Angela R, Mayfield R D, Ponomarev Igor, Jones Theresa A, Blednov Yuri A, Harris R A

Abstract excerpt

BACKGROUND: The inability to reduce or regulate alcohol intake is a hallmark symptom for alcohol use disorders. Research on novel behavioral and genetic models of experience-induced changes in drinking will further our knowledge on alcohol use disorders. Distinct alcohol self-administration behaviors were previously observed when comparing two F1 hybrid strains of mice: C57BL/6J x NZB/B1NJ (BxN) show reduced...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23102405
DOI: 10.1186/1471-2202-13-130
PMCID: PMC3504532

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